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The active component of Ambien, zolpidem, is a hypnotic that affects the central nervous system. Its principal mode of action is to increase GABA's inhibitory signaling, which is the primary neurotransmitter that lowers neuronal excitability throughout the nervous system. Ambien, in contrast to conventional benzodiazepines, binds specifically to the omega-1 receptor, a subgroup of GABA receptors. Without substantially altering the architecture of sleep stages, this selective binding aids in the onset of sleep.
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